國際間質幹細胞臨床研究
美國國家生物技術訊息中心(NCBI) 臨床研究/ 論文發表
中風
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Reparative therapy for acute ischemic stroke with allogeneic mesenchymal stem cells from adipose tissue:a safety assessment: a phase II randomized, double blind, placebo-controlled, single-center, pilot clinical trial.
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軟骨修復
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Safety of autologous bone marrow-derived mesenchymal stem cell transplantation for cartilage repair in 41 patients with 45 joints followed for up to 11 years and 5 months.
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乳房重建
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Cell-assisted lipotransfer for cosmetic breast augmentation: supportive use of adipose-derived stem/stromal cells.
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糖尿病I型
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Preserved β-cell function in type 1 diabetes by mesenchymal stromal cells.
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糖尿病II型
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Efficacy and safety of autologous bone marrow-derived stem cell transplan- tation in patients with type 2 diabetes mellitus: a randomized placebo-con- trolled study.
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腎臟移植
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Induction therapy with autologous mesenchymal stem cells in living-related kidney transplants: a randomized controlled trial.
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移植物抗宿主疾病
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Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study.
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帕金森氏症
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Open-labeled study of unilateral autologous bone-marrow-derived mesenchymal stem cell transplantation in Parkinson's disease.
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肝硬化
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Human umbilical cord mesenchymal stem cells improve liver function and ascites in decompensated liver cirrhosis patients.
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多發性硬化症
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Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study.
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紅斑性狼瘡
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Allogeneic mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus: 4 years of experience.
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男性性功能障礙
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The Current Status of Stem-Cell Therapy in Erectile Dysfunction: A Review
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資料來源:美國國家生物技術訊息中心(NCBI)
脂肪間質幹細胞參考文獻
脂肪組織含有豐富間質幹細胞,且細胞具有高度分化能力

Indian J Plast Surg. 2018 May-Aug;51(2):177-181. doi: 10.4103/ijps.IJPS_150_17.
Adipose tissue: A natural resource for multipotent mesenchymal stem cellswith potential translation to trigerminal layers.
退化性關節炎臨床案例 (軟骨新生變化)

Stem Cells Transl Med. 2016 Jul;5(7):847-56. doi: 10.5966/sctm.2015-0245. Epub 2016 May 23.
Adipose Mesenchymal Stromal Cell-Based Therapy for Severe Osteoarthritis of the Knee: A Phase I Dose-Escalation Trial.
資料來源:美國國家生物技術訊息中心(NCBI)
間質幹細胞相關報導
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自由時報 1 0 7 . 5 . 6
北榮和台大醫院更進一步研究發現,間質幹細胞可分泌大量細胞激素,進而增進胚胎滋養層細胞的移動能力。另外,這些激素富含生長因子與細胞激素,的確有助於修補子宮內膜,進而增加著床率。
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自由時報 1 0 3 . 8 . 1 0
英國倫敦帝國學院一項研究顯示,幹細胞治療可促進腦部受損區血管新生。5 名中風患者在接受治療後, 明顯改善說話、行動與認知能力。
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自由時報 1 0 2 . 7 . 3 0
國衛院與國防醫學院研究發現,間質幹細胞可藉由分泌肝臟生長因子(HGF),抑制身體過度的免疫反應,未來可應用於自體免疫疾病的治療。
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自由時報 1 0 3 . 1 1 . 2 6
臺北醫學大學動物實驗研究發現,間質幹細胞可維持小腦萎縮症小鼠腦部功能及延緩病程。目前已通過一期人體臨床安全性試驗,未來有望納入療程。
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